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Effect of Hydrogen on Post - herpetic Neuralgia: A Randomized Controlled Clinical Trial

Effect of Hydrogen on Post - herpetic Neuralgia: A Randomized Controlled Clinical Trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-INR-17010337
Enrollment
Unknown
Registered
2017-01-05
Start date
2017-01-02
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postherpetic neuralgia

Interventions

Control group:Oxygen inhalation 3L / min
Hydrogen treatment group:Hydrogen and oxygen inhalation

Sponsors

Second Hospital of Tianjin Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. post-herpetic neuralgia patients line in with diagnostic criteria: Pain duration more than three months after herpes zoster cure, the distribution of nerve involvement with severe spontaneous pain or pain-like attacks etc., accompanied by pain or abnormal sensitivity to pain; 2. oral drug treatment was ineffective or can not tolerate adverse reactions, age greater than 18 years; 3. 24 hours of average pain score greater than 4 points.

Exclusion criteria

Exclusion criteria: 1. does not meet the PHN diagnosis criteria, and with severe heart, liver and kidney dysfunction; 2. infection, history of malignancy; 3. mental illness or disturbance of consciousness can not cope with treatment, articulate expression is not clear; 4. suffering from respiratory diseases, respiratory insufficiency.

Design outcomes

Primary

MeasureTime frame
visual analogue scale;

Secondary

MeasureTime frame
Hyperalgesia;Sleep rating;The amount of analgesic drugs;malondialdehyde;Superoxide dismutase;Interleukin-6;Hypoxia inducible factor-1a;

Countries

China

Contacts

Public Contactyu yonghao

Second Hospital of Tianjin Medical University

yuyonghao@163.com+86 13920590099

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026