Postherpetic neuralgia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. post-herpetic neuralgia patients line in with diagnostic criteria: Pain duration more than three months after herpes zoster cure, the distribution of nerve involvement with severe spontaneous pain or pain-like attacks etc., accompanied by pain or abnormal sensitivity to pain; 2. oral drug treatment was ineffective or can not tolerate adverse reactions, age greater than 18 years; 3. 24 hours of average pain score greater than 4 points.
Exclusion criteria
Exclusion criteria: 1. does not meet the PHN diagnosis criteria, and with severe heart, liver and kidney dysfunction; 2. infection, history of malignancy; 3. mental illness or disturbance of consciousness can not cope with treatment, articulate expression is not clear; 4. suffering from respiratory diseases, respiratory insufficiency.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| visual analogue scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hyperalgesia;Sleep rating;The amount of analgesic drugs;malondialdehyde;Superoxide dismutase;Interleukin-6;Hypoxia inducible factor-1a; | — |
Countries
China
Contacts
Second Hospital of Tianjin Medical University