Acute Drug-Induced Liver Injury by Anti-AIDS Drugs (Gan-Dan Damp-Heat Syndrome and Qi-Blood Deficiency Syndrome)
Conditions
Interventions
Control group:Compound Glycyrrhizin Capsules
Sponsors
Beijing Ditan Hospital Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Compliance with HIV/AIDS diagnostic criteria; 2. Aged 18-65 years old, male or female; 3. In accordance with the diagnostic criteria for drug-induced liver injury, and meet the following conditions: (1) Course of disease is less than 3 months; (2) ALT or AST < 5 ULN; (3) TBil < 2.5 ULN; (4) INR < 1.5; (5) PTA = 60%; (6) Eosinophils < 5%; 4. In accordance with the Gan-Dan Damp-Heat Syndrome and Qi-Blood Deficiency Syndrome performance; 5. The voluntary randomized controlled study, signed informed consent, can be regular follow-up.
Exclusion criteria
Exclusion criteria: 1. Patients with acute or subacute liver failure or severe liver injury; 2. The HAV, HBV, HCV, HEV, EBV, CMV infection and fatty liver (alcoholic and non-alcoholic), cirrhosis, liver cancer, autoimmune liver disease, cholestatic disease and genetic metabolic liver disease and other non drug factors of liver injury; 3. The heart failure, hypotension, shock, non drug induced factors of vascular occlusive disease; 4. The pregnancy and breast-feeding women, or ready for pregnant women; 5. The patients with the disorders of the intelligence or language, psychiatric patients; 6. Patients attending other clinical trials; 7. The allergy; 8. The investigators think the situation is not suitable for other researchers in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| liver function test;TCM syndrome scores; | — |
Countries
China
Contacts
Public ContactLi Xin
Beijing Ditan Hospital Capital Medical University
Outcome results
None listed