Cerebral palsy
Conditions
Interventions
Control group:No intervention
HCP+CIMT:Constraint-induced Movement Therapy
HCP+OT:Occupational therapy
Sponsors
Guangzhou Women and Children's Medical Center
Eligibility
Sex/Gender
All
Age
3 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1. meet the diagnostic and classification criteria of HCP; 2. aged 3-12 years old; 3. suffering from a small range of anti-gravity activities, suffering from wrist dorsiflexion = 20 degree, metacarpophalangeal joint stretch = 10 degree; 4. functional differences of 20 % - 80%; 5. have a certain cognitive ability to understand the simple instructions, parents can cooperate with the study and sign the consent form.
Exclusion criteria
Exclusion criteria: 1. suffering from other diseases not associated with cerebral palsy, uncontrolled seizures; 2. ipsilateral upper limb fixed contracture or deformity, received in the last 6 months or during the study period to prepare for orthopedic surgery, botulinum toxin injection, Are receiving baclofen, An Tan and other treatment; 3. due to sensory dysfunction caused by neglected side, the impact of rehabilitation intervention and assessment of visual and balance disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nogo-A protein; | — |
Secondary
| Measure | Time frame |
|---|---|
| NgR1 receptor;Rho-A receptor;the ROCK gene;ROCK controls expression of proteins; | — |
Countries
China
Contacts
Public ContactKaishou Xu
Guangzhou Women and Children's Medical Center
Outcome results
None listed