Rheumatoid Arthritis
Conditions
Interventions
treatment group:MTX+Wen yang tong luo granule
Sponsors
The First Hospital Affiliated to Henan University of TCM
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) in line with Western diagnostic criteria of RA, DAS score = 3.2, duration = 36 months; (2) in line with diagnostic criteria for TCM syndrome; (3) Aged during 18-65 years old; (4) joint function in grade I-III and X-ray staging in stage I-III; (5) Patients receiving oral glucocorticoids treated with prednisone (=10mg/d) or equal amounts of hormones (eg, methylprednisolone 8mg) were stable for at least 30 days prior to study entry. If not taking the hormone, then at least 30 days has not been served; (6) If taking NSAIDs (non-steroidal anti-inflammatory drugs) patients, need to stop using at least 7 days or more; (7) Patients who have not previously used DMARDs or have long-term use of methotrexate should be discontinued for 3 months or longer if DMARDs (other than methotrexate) are prescribed; (8) Sign the informed consent of the clinical study.
Exclusion criteria
Exclusion criteria: (1) overlap with other rheumatism, such as systemic lupus erythematosus, Sjogren's syndrome, severe knee osteoarthritis and so on; (2) merger of heart, brain, liver, kidney and hematopoietic system, such as serious illness; (3) pregnant or lactating women, psychiatric patients; (4) those who are allergic; (5) those who are participating in other clinical trials of patients; (6) taking methotrexate useless ruled out; (7) on the side of Warming yang and Smoothening Meridians prescription and allergic to methotrexate ruled out; (8) recent fertility requirements were excluded; (9) The use of biological DMARDs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ACR20 improvement rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| ACR50 improvement rate;ACR70 improvement rate;DAS28;CDAI;SDAI;Curative effect of traditional Chinese Medicine;Curative effect of Chinese medicine syndrome;Evaluation of the quality of life in patients; | — |
Countries
China
Contacts
Public ContactJiangyun Peng
Yunnan Provincial Hospital of traditional Chinese Medicine
Outcome results
None listed