Dental caries
Conditions
Interventions
two groups:arginine-free/arginine-containing toothpaste
Sponsors
West China Hospital of Stomatology, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 27 Years
Inclusion criteria
Inclusion criteria: Subjects were categorized into two groups. The caries-free (CF) group consisted of 6 individuals with no clinical evidence of caries experience [decayed, missing and filled teeth (DMFT = 0)]. The caries-active (CA) group consisted of 6 individuals with decayed, missing and filled teeth (DMFT > 6).
Exclusion criteria
Exclusion criteria: smoker or former smoker, presence of any systemic disease that could alter the production or composition of the saliva, treatment with antibiotics, steroids or any medication known to cause dry mouth in the last 3 months, and presence of dental prostheses or orthodontic devices that might affect the oral environment. arginine-free or arginine-containing toothpaste
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lactic acid production;MTT assay;SEM imaging;Live/dead staining; | — |
Countries
China
Contacts
Public ContactXue Yiyuan
West China Hospital of Stomatology, Sichuan University
Outcome results
None listed