Rotator cuff tendinopathy
Conditions
Interventions
PRP group:subacromial injection of 5 ml platelet-rich plasm per week, total two injections
Control group :subacromial injection of 5 ml saline per week, total two injections
Sponsors
Hong-hui Hospital, Xi'an Jiaotong University College of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with shoulder impingement syndrome or a partial-thickness rotator cuff tear; 2. Diagnosis based on MRI; 3. Male or female, aged 35 to 75 years old.
Exclusion criteria
Exclusion criteria: 1. Full thickness rotator cuff tears; 2. Participants with a history of significant trauma.(fracture, dislocation, instability and so on), surgery, osteoarthritis or other significant pathology of the affected shoulder not related to the rotator cuff; 3. Patient is unable to consent; 4. History of injection treatment of shoulders; 5. Contraindications to PRP (listed below). PRP contraindications: 1. History of diabetes mellitus; 2. Platelet abnormality or platelet count <100×10^9/l; 3. Hematological disorder; 4. Serum hemoglobin <11 g/dl; 5. Use of systemic cortisone; 6. Use of any anticoagulant; 7. Evidence of gangrene, ulcers or peripheral vascular disease; 8. History of hepatic or renal impairment or dialysis; 9. Patient is known to have a psychological, developmental, physical, emotional or social disorder that may interfere with compliance with study requirements; 10. History of alcohol or drug abuse; 11. Patient has a religious or cultural conflict with the use of platelet gel or blood products; 12. Patient has inadequate venous access for blood draw; 13. Patient is currently receiving or has received radiation or chemotherapy within the last 3 months prior to the study; 14. Female participants who are pregnant, lactating or planning pregnancy during the course of the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Shoulder pain and disablity index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Constant-Mulary score for shoulder function;Oxford shoulder score;visual analogue scale for pain;range of motion;subjective satisfaction of patients; | — |
Countries
China
Contacts
Public ContactHui Kang
Hong-hui Hospital, Xi'an Jiaotong University College of Medicine
Outcome results
None listed