Coronary atherosclerotic heart disease
Conditions
Interventions
Conventional ECC Group:using conventional ECC system during CABG
Modified MECC Group:using modified MECC system during CABG
Sponsors
Department of Cardiovascular Surgery, Shanghai Tenth People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: All patients undergoing on-pump CABG: for male, LVEF 58mm;for female, LVEF 55mm; severe LM lesion; Syntax score > 32; NYHA III or IV; unstable angina or heart failure onset under adequate medications.
Exclusion criteria
Exclusion criteria: CAD patients combined with ventricular aneurysm or heart valve disease which needs to be treated during the surgery; existing end organ dysfunction such as COPD, CKD, peripheral neural and vascular disease related to DM
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| number of grafts;duration of intubation;length of ICU stay;chest tube drainage in the first post-op 24hrs;blood products consumption;cTnI, N-proBNP, IL-33, sST2;NGAL, KIM-1, Cystatin-C;ET-1, EMP;IL-2, IL-6, Lac;plasma colloid osmotic pressure;plasma ALB concentration;plasma HB concentration;NYHA classification in1-year follow-up;LVEF at1-year follow-up;Grafts patency at 1-year follow-up; | — |
Countries
China
Contacts
Public ContactZhou Jian
Shanghai Tenth People's Hospital
Outcome results
None listed