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Local anesthetic infiltration with different concentration of dexmedetomidine cocktail and continuous femoral nerve block in postoperative analgesia of total knee arthroplasy: a prospective randomized controlled study

Local anesthetic infiltration with dexmedetomidine cocktail and continuous femoral nerve block in postoperative analgesia of total knee arthroplasy: a prospective randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-INR-16009825
Enrollment
Unknown
Registered
2016-11-11
Start date
2016-12-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis

Interventions

Continuous femoral nerve block:Continuous femoral nerve block
local anesthetic infiltration:local anesthetic infiltration

Sponsors

Peking University Third Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. primary unilateral total knee arthroplasty; 2. aged 18 years and more; 3. ASA grade I to III.

Exclusion criteria

Exclusion criteria: 1. bilateral unilateral total knee arthroplasty; 2. after patellatomy; 3. pregnancy; 4. acute of chronic knee infection; 5. neuromuscular disease involving lower limbs; 6. severe systemic disease (eg. heart failure, renal insufficiency, coagulopathy); 7. cognitive function deficits or mental disorders; 8. contraindication of spinal anesthesia; 9. long-term use of narcotics; 10. allergy to drugs used in the study; 11. refuse to sign consent.

Design outcomes

Primary

MeasureTime frame
Visual analogue scale at rest;Consumption of opioids;Visual analogue scale at activity;—

Secondary

MeasureTime frame
Range of motion;Ability to do straight leg raising on POD 1;Ability to do straight leg raising on POD 2;Ability to do extension of knee on POD1;Ability to do extension of knee on POD2;Length of stay;Visual analogue scale at rest;Visual analogue scale at activity;Visual analogue scale at rest;Visual analogue scale at activity;Range of motion;Range of motion;Ability to stand on POD1;—

Countries

China

Contacts

Public ContactXu Mao
anae@163.com+86 18911482830

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026