diarrhea type irritable bowel syndrome
Conditions
Interventions
MachixianJianpiFang group:Chinese medicinal decotion of MachixianJianpiFang
Gegenqinlian modified decoction group:Gegenqinlian modified decoction
Sponsors
Department of Traditional Chinese Medicine, Changhai hospital, The Second Military Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 65 years; 2. In line with Western medicine diagnostic criteria of IBS-D; 3. In line with Chinese medicine diagnostic criteria of spleen-stomach damp-heat syndrome; 4. Baseline IBS-SSS score>75; 5. Participants or legal representatives informed,and freely give informed consent.
Exclusion criteria
Exclusion criteria: 1. Taking part in other clinical trials; 2. Having organic lesion with digestive system or systemic disease that can influence the motility of digestive tract.For example,hyperthyroidism,diabetes and chronic renal insufficiency; 3. Be combined with serious primary diseases of liver, kidney, hematopoietic system, heart and cerebral vessels.Or seriously affect their survival.For example,HIV and malignant tumors; 4. With a history of abdominal surgery(For example,cholecystectomy); 5. With nervous system diseases and a history of mental trouble; 6. To participate in the test have taken or need to continue with drug that may be affect gastrointestinal function within 2 weeks before(For example,anticholinergics,calcium antagonists,receptor antagonists of 5-HT3,obstruents,antacids,prokinetics,antidepressants,antianxietics and intestinal flora regulators); 7. Pregnant or lactating women; 8. With allergy history of drug which is used in this research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Irritable bowel syndrome symptom severity score;Irritable bowel syndrome-quality of life questionnaire; | — |
Countries
China
Contacts
Public ContactPeng Hao
Department of Traditional Chinese Medicine, Changhai hospital, The Second Military Medical University
Outcome results
None listed