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The Effect of flurbiprofen axetil in patients undergoing total knee arthroplasty: A Prospective, Randomized, Controlled Trial

The Effect of flurbiprofen axetil in patients undergoing total knee arthroplasty: A Prospective, Randomized, Controlled Trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-INR-16009758
Enrollment
Unknown
Registered
2016-11-07
Start date
2016-11-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

osteoarthritis

Interventions

Group A:Routine pain control
Group B:Routine pain control and flurbiprofen axetil

Sponsors

West China Hospital, Sichuan university
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients aged 18 years and older scheduled for a primary TKA because of the end-staged osteoarthritis.

Exclusion criteria

Exclusion criteria: Exclusion criteria included revisions, bilateral procedures, previous knee surgery history, flexion deformity=30 degree, varus/valgus deformity=30 degree, anemia (<120 g/L for female, <130 g/L for male), contraindications for the use of TXA and coagulation disorders.

Design outcomes

Secondary

MeasureTime frame
lower limb swelling ratio;CRP;IL-6;the length of hospital stays;patient satisfaction;complications;—

Primary

MeasureTime frame
VAS pain score;Opioid cummsuption;—

Countries

China

Contacts

Public ContactFuxing Pei

West China Hospital, SiChuan University

peifuxing1952@163.com+86 13551068711

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026