refractory gastroesophageal reflux disease
Conditions
Interventions
Group of TCM syndrome differentiation + PPI :TCM syndrome differentiation + PPI
Group of Agreement prescription of traditional Chinese Medicine+PPI: Agreement prescription of traditional Chinese Medicine+PPI
Sponsors
Shanghai Yueyang Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) In accordance with gastroesophageal reflux disease western medicine and traditional Chinese medicine diagnostic criteria; (2) The failed treated gastroesophageal reflux disease by taken the first generation of PPI continuely for four weeks or longer in the present study; (3) Aged 18-70 years male or female.
Exclusion criteria
Exclusion criteria: 1) With one of the following diseases: peptic ulcer, esophageal and gastric and duodenal surgery, Zollinger Ellison syndrome, primary esophageal motility disorders (such as achalasia, scleroderma, primary esophageal spasm), upper gastrointestinal malignant lesions, drug esophagitis, and psychiatric patients. 2) Pregnant women and lactating women; 3) The liver and kidney function is obviously abnormal (AST, ALT, the creatinine value is higher than the normal value range one and a half); 4) The person who can not cooperate with the treatment, can not take medicine on time and carry on the related examnation; 5) The patients themselves are directly involved in the research of the clinical research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Safety index;Effect index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation index; | — |
Countries
China
Contacts
Public ContactWANG XIAOSU
Shanghai Yueyang Hospital
Outcome results
None listed