tuberculosis
Conditions
Interventions
Sponsors
Shanghai Pulmonary Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. newly diagnosed untreated pulmonary tuberculosis patients with positive sputum smear; 2. radiological examination of the lungs with lesions; 3. aged between 18 and 65 years; 4. the fasting blood glucose is less than 7.0mmol/L; 5. sputum smear positive, confirmed is Mycobacterium tuberculosisby by MTB/RIF GeneXpert detection sputum culture positive, the identification of bacteria type identification of Mycobacterium tuberculosis. 6. To be able to understand and sign the informed consent form; 7. DST results showed that the first line four drug were all sensitive or only HR resistant multi drug resistant tuberculosis patients.
Exclusion criteria
Exclusion criteria: 1. Pulmonary tuberculosis complicated with extrapulmonary tuberculosis (except tuberculous pleurisy not develop tuberculous empyema); 2. Allergic to any drug in the program; 3. Combined liver, kidney, metabolism, autoimmune diseases, endocrine, blood, nervous system diseases, mental disease, malignant tumor, long-term use of immunosuppressive agents or HIV/AIDS patients; 4. Alcoholics (>10year, and >100g liquor daily); 5. According to the researchers' judgment, patients who are not suitable for the study or who may not be able to reliably participatethe whole course of the study; 6. to participate in other clinical research at the same time; 7. Poor compliance history in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cure rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Recurrence rate;radiologic improvement rate; | — |
Countries
China
Contacts
Public ContactSha Wei
Shanghai Pulmonary Hospital
Outcome results
None listed