Schizophrenia
Conditions
Interventions
CHR with real rTMS:real personalized rTMS
CHR with sham rTMS:sham rTMS
FES with real rTMS:real rTMS
FES with sham rTMS:sham rTMS
HC:no intervention
Sponsors
Shanghai Mental Health Center
Eligibility
Sex/Gender
All
Age
15 Years to 45 Years
Inclusion criteria
Inclusion criteria: Clinical high-risk for psychosis (CHR): meeting the criteria for CHR mental state as defined by the Structured Interview for Prodromal Syndromes (SIPS) and the Scale of Prodromal Syndromes (SOPS); aged between 15-45 years old; IQ>69; no substance or alcohol abuse within recent three months; no DSM-V axis I disorders; no prior psychopharmacological treatment. First-episode schizophrenia: meeting the criteria for schizophrenia as defined by DSM-V; age between 15-45 years old; IQ>69; PANSS>=60; CGI>=4; no other DSM-V axis I disorders; no prior psychopharmacological treatment. Healthy controls: no mental disorders screened using SIPS/SOPS and SCID; age between 15-45 years old; IQ>69; no history or family history of mental disorders; no substance or alcohol abuse.
Exclusion criteria
Exclusion criteria: Sensory/motion disorders (e.g., hearing disorders, blindness), neurological illness (brain injury, epilepsy), or other severe somantic illness which can lead to clinical high-risk symptoms; claustrophobia, with metallic objects in their head or any type of stimulator in their body
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CHR SIPS/SOPS scores;FES PANSS scores;MCCB scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| Social cogntive function; | — |
Countries
China
Contacts
Public ContactJijun Wang
Shanghai Mental Health Center
Outcome results
None listed