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Pain assessment in conscious healthy volunteers: a cross-over study for the evaluation of the analgesia nociception index

Pain assessment in conscious healthy volunteers: a cross-over study for the evaluation of the analgesia nociception index

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-INR-16009356
Enrollment
Unknown
Registered
2016-10-10
Start date
2016-10-17
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

PAIN

Interventions

A:lidocaine cream first, then give VE cream
B:VE cream first, then Lidocaine cream

Sponsors

Peking University People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 39 Years

Inclusion criteria

Inclusion criteria: (1) Aged 18-39 years old; BMI 18-25kg/m2; (2) Healthy volunteers:normal vital signs(body temperature, pulse rate, respiration, blood pressure);corrected visual acuity >0.8;normal exercise tolerance (can climb four flights of stairs); (3) No sensory impairments on the right volar forearm and no scars; and (4) Voluntarily accept the trial and sign informed consent.

Exclusion criteria

Exclusion criteria: (1) Volunteers who are allergic to local anesthetic or VE cream or have taken drugs affecting heart rate recently or have arrhythmias; (2) Female volunteers in menstruation, pregnancy or lactation period; (3) People with previous liver and kidney disease history; (4) People in anxiety state or their SAS indicates anxiety; (5) People with mental or neurological diseases.

Design outcomes

Primary

MeasureTime frame
ANI;

Countries

China

Contacts

Public ContactFENG Yi

Peking University People's Hospital

yifeng65@sina.com+86 13601083503

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026