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A randomized controlled clinical trial on the treatment of microwave ablation versus anhydrous alcohol in patients with thyroid cystic nodules

A randomized controlled clinical trial on the treatment of microwave ablation versus anhydrous alcohol in patients with thyroid cystic nodules

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-INR-16009182
Enrollment
Unknown
Registered
2016-09-10
Start date
2017-07-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid nodules

Interventions

Anhydrous alcohol:Anhydrous alcohol injection

Sponsors

PLA 323th Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Cystic or predominantly cystic thyroid nodule (> 80%); 2. Nodal diameter > 2 cm; 3. The patient has not been treated by radioactive iodine, TSH suppression therapy, etc; 4. Ultrasound revealed no characteristics of malignant nodules; 5. The patient's own conditionTheir own conditions can't tolerance to traditional surgery, or the patient reject the traditional surgery; 6. Including one of the following situations: nodule visibly increased, local symptoms, such as foreign body sensation, neck discomfort; nodules affect appearance so the patient required treatment; patients thought concerns is overweight and their normal life is affected; 7. Voluntary participation in clinical trials and signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Ultrasound prompted the possibility of malignant nodules; 2. Lesions of contralateral vocal cord dysfunction; 3. Severe coagulation disorders; 4. Serious heart, cerebrovascular diseases, respiratory diseases, liver and kidney dysfunction complications, such as intolerance to treatment; 5. Refused to participate in this experiment or refuse to sign the informed consent; 6. Suspend the standard of clinical trials; 7. Do not accord with standard of cases into the group; 8. Asked to quit the study; 9. Intraoperative complications appeared in the process of treatment led to the suspension of therapy; 10. Researchers from the medical point of view that the subjects need to be to suspend the test.

Design outcomes

Primary

MeasureTime frame
Volume reduction ratio;

Secondary

MeasureTime frame
Complications;Blood score;The recurrence rate;

Countries

China

Contacts

Public ContactJianbo Shuang

PLA 323th Hospital

jbshuang@126.com+86 18966717894

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026