uterine fibroid
Conditions
Interventions
group L:lidocaine 1.5mg/kg was intravenous injected before anesthesia induction, lidocaine 2mg/kg.h was continuous infusion after intubation
group D:Dexmedetomidine 1ug/kg was intravenous injected before anesthesia induction, dexmedetomidine 0.4ug/kg.h was continuous infusion after intubation
group C:Equivalent saline was intravenous injected before anesthesia induction and continuous infusion after intubation
Sponsors
Department of Anesthesiology, West China Second Hospital of Sichuan University
Eligibility
Sex/Gender
Female
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Patients undergoing elective gynecological laparotomy (abdominal hysterectomy myomectomy or hysterectomy), ASA I-II, aged 18-60 years, and the operation time is 1-6h.
Exclusion criteria
Exclusion criteria: Local anesthetic allergy, arrhythmia or long-term use of anti-arrhythmic drugs, pathological bladder, morbid obesity, severe liver and kidney dysfunction, heart failure, chronic pain, long-term use of opioids. Intraoperative bleeding or postoperative bleeding underwent secondary surgery, severe intraoperative allergic reactions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence of CRBD;severity of CRBD; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS score;sedation score;postoperative recovery time of gastrointestinal function;postoperative adverse reactions; | — |
Countries
China
Contacts
Public ContactNi Juan
Department of Anesthesiology, West China Second Hospital of Sichuan University
Outcome results
None listed