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Prokinetic agents combined with remedial bedside blind intubation to improve the success rate of post-pyloric placement of spiral nasojejunal tubes in critically ill patients: a multi-center, prospective, randomized-controlled trial

Prokinetic agents combined with remedial bedside blind intubation to improve the success rate of post-pyloric placement of spiral nasojejunal tubes in critically ill patients: a multi-center, prospective, randomized-controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-INR-16009099
Enrollment
Unknown
Registered
2016-08-26
Start date
2016-09-01
Completion date
Unknown
Last updated
2018-07-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

self-propelled feeding tubes insertion

Interventions

Prokinetic agents combined with remedial bedside blind intubation group:Prokinetic agents combined with remedial bedside blind intubation
Prokinetic agents group:Prokinetic agents (metoclopramide hydrochloride injection or domperidone suspension)

Sponsors

Guangdong General hospital, Guangdong Academy of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. aged older than 18 years; 2. admitted to ICU; 3. requiring enteral nutrition support for more than 3 days; 4. gastric residual volume increased (single measurement > 150ml or cumulative volume in 12 hours > 500ml); 5. informed consent has been signed.

Exclusion criteria

Exclusion criteria: 1. Indications of percutaneous gastrostomy or jejunostomy; 2. esophageal varices or strictures, or previous major gastro-esophageal surgery (for example; 3. activity of the upper digestive tract hemorrhage; 4. serious injury or stenosis of nasopharynx; 5. severe coagulation disorder; 6. malignant tumor, peptic ulcer of the stomach or intestinal mechanical obstruction; 7. pregnant; 8. contraindication of domperidone and metoclopramide; 9. history of allergy to meglumine diatrizoate.

Design outcomes

Primary

MeasureTime frame
success rate of post-pyloric placement of spiral nasaljejunal tubes;

Secondary

MeasureTime frame
time for tube insertion;attempts;time between decision of tube placement and the beginning of enteral nutrition;X rays related to tube placement;cost related to tube placement;

Countries

China

Contacts

Public ContactChunbo Chen

Guangdong General Hospital, Guangdong Academy of Medical Sciences

gghicu@163.com+86 13922745788

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 8, 2026