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The security and effect of atropine applied in the painless gastrointestinal endoscopy with target-controlled infusion of propofol and low dose of sufentanil:A prospective randomized controlled single-blinded clinical trial

The security and effect of atropine applied in the painless gastrointestinal endoscopy with target-controlled infusion of propofol and low dose of sufentanil:A prospective randomized controlled single-blinded clinical trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-INR-16009024
Enrollment
Unknown
Registered
2016-08-14
Start date
2016-08-15
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastrointestinal endoscopy

Interventions

Control group:sufentanil 0.05ug/ml + NS 2 ml
Atropine group:sufentanil 0.05ug/ml + atropine 0.5mg resolve in 2ml NS

Sponsors

The 2nd Affiliated Hospital of Wenzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. undergoing gastrointestinal endoscopy; 2. Aged 18-65 years old; 3. BMI 18 to 26kg/m2; 4. obtain written informed consent; 5. the same endoscopist.

Exclusion criteria

Exclusion criteria: 1. be allergic to propofol; 2. have ever suffered from glaucoma or prostatomegaly; 3. suffered from diabetes and hyperthyreosis; 4. tachycardia and other arrhythmia; 5. have ever suffered from abdominal operation; 6. liver and kidney dysfunction; 7. plan to be conducted endoscopic treatment.

Design outcomes

Primary

MeasureTime frame
blood pressure;The time consumption from colonoscope placed into anus to colonoscope reached the ileocecal valve;time consumption of gastroscopy;D-Value (MAP between the time before induction and the end of induction);

Secondary

MeasureTime frame
the satisfaction degree of endoscopist;the satisfaction degree of patients;

Countries

China

Contacts

Public ContactRuifeng Zeng

Department of Anesthesiology, The 2nd Affiliated Hospital of Wenzhou Medical University

ruifengzeng@163.com+86 13857734776

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026