FindTrial
Sign In

Low-dose Electroconvulsive Therapy (LET) for Major Depressive Disorder: A randomized, Double-blind, Comparative Trial

Low-dose Electroconvulsive Therapy (LET) for Major Depressive Disorder: A randomized, Double-blind, Comparative Trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-INR-16008993
Enrollment
Unknown
Registered
2016-08-08
Start date
2016-09-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression Disorder

Interventions

Low-dose ET group:Low-dose ET+regular pharmacotherapy
Regular ECT group:Regular ECT+regular pharmacotherapy

Sponsors

Shenzhen Mental Health Center (Shenzhen Kangning Hospital)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. aged from 18 to 60 years; 2. unipolar or bipolar depression patients with or without psychotic symptoms according to DSM-5 diagnostic criteria; 3. Signed consent forms; 4. HAMD-17>16.

Exclusion criteria

Exclusion criteria: 1. pregnancy; 2. participated in other related studies in 30 days; 3. accepted ECT or rTMS treatment in 6 months; 4. history of psychoactive substance abuse; 5. exists ECT-related contraindications; 6. exists anesthesia risk of cardiovascular disease; 7. history of epilepsy; 8. high suicide risk before admission.

Design outcomes

Primary

MeasureTime frame
Hamilton depression Rating Scale, HAMD;—

Secondary

MeasureTime frame
the Positive and Negative Syndrome Scale, PANSS;Working Memory Test;Autobiographical Memory Test, AMT;Montreal Cognitive Assessment, MoCA;—

Countries

China

Contacts

Public ContactMin-zhi Li

Shenzhen Mental Health Center (Shenzhen Kangning Hospital)

23887099@163.com+86 13510095413

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026