prediabetes
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Fulfill prediabetes diagnostic criteria; 2. Aged 18-50; 3. Completed and submitted informed consent form.
Exclusion criteria
Exclusion criteria: 1. History of diabetes (except gestational diabetes); 2. Cardiovascular events (cerebrovascular accident in 6 months, history of myocardial infarction or heart failure; severe organic heart disease; aneurysm with the main artery or dissecting aneurysm; specific angina, type II degree atrioventricular block, sick sinus syndrome); 3. Serious impairment of hepatic and renal function: ALT 2- fold the upper limit of normal or above; same for BUN and creatinine; 4. Endocrine disease, such as hyperthyroidism, autoallergic disease, cancer or other serious fatal illness; 5. Pregnancy, preparation of pregnancy and lactating women; 6. Suffering from mental diseases or non-cooperation patients; 7. Participating in other clinical trial; 8. People refusing to provide consent for the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting plasma glucose (FPG) level; | — |
Secondary
| Measure | Time frame |
|---|---|
| 2-h plasma glucose (2hPG) level after a 75-g oral glucose tolerance test (OGTT);Glycosylated hemoglobin (HbA1c);Middle shear rates of whole-blood viscosity (30/S);Low shear rates of whole-blood viscosity (10/S);Low shear rates of whole-blood viscosity (1/S);Plasma viscosity; | — |
Countries
China
Contacts
The fifth affiliated hospital of Guangzhou medical university