acute leukemia
Conditions
Interventions
experimental group A:cotransplantation of haploidentical peripheral blood stem cells and mesenchymal stem cells (d0)
experimental group B:cotransplantation of haploidentical peripheral blood stem cells and mesenchymal stem cells (d+30)
control group:haploidentical peripheral blood stem cell transplantation
Sponsors
The first affiliated hospital of Xi'an jiaotong university
Eligibility
Sex/Gender
All
Age
14 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. Acute leukemia patients (including AML and ANML) at first complete remission before transplantation; 2. HLA matching of the donor and the patients was haploidentical; 3. Patients recieved allogeneic hematopoietic stem cell transplantation in our hospital from January 2016 to December 2019.
Exclusion criteria
Exclusion criteria: 1. Patients aged 14~55 years old; 2. Patients don't achieve remission; 3. Patients with heart,lung or kidney dysfunction; 4. Patients with mental disorders; 5. Pregnancy patients with leukemia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| overall survival;rate of relapse; | — |
Secondary
| Measure | Time frame |
|---|---|
| rate of graft;rate of aGVHD and cGVHD; | — |
Countries
China
Contacts
Public ContactHE PENGCHENG
The first affiliated hospital of Xi'an jiaotong university
Outcome results
None listed