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Use of Tranexamic Acid (TXA) on the effects of perioperative blood loss during posterior orthopedic fusion surgery in adult degenerative scoliosis

Use of Tranexamic Acid (TXA) on the effects of perioperative blood loss during posterior orthopedic fusion surgery in adult degenerative scoliosis,a randomized controlled study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-INR-16008375
Enrollment
Unknown
Registered
2016-04-27
Start date
2016-04-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

adult degenerative scoliosis

Interventions

The tranexamic acid group:Preoperative use of tranexamic acid
The control group:Physiological saline

Sponsors

Honghui Hospital,Xi’an Jiao tong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Conforms to the diagnostic criteria of adult degenerative scoliosis patients; 2. ADS patients who accept the orthopaedic arthrodesis.

Exclusion criteria

Exclusion criteria: 1. Patients with hemorrhagic disease; 2. The platelet count is less than 100x10^9/L; 3. Patients of coagulant function abnormality; 4. Before patients had embolism events or family history of thrombosis disease; 5. With severe medical problems can't tolerate surgery.6.Patients allergic to tranexamic acid; 7. Patients with Congenital scoliosis or adolescent idiopathic scoliosis.

Design outcomes

Primary

MeasureTime frame
Perioperative blood loss;Perioperative blood transfusion;hematokrit;Blood coagulation system;The operation time;Age;Gender;Blood clots;Hemoglobin;—

Countries

China

Contacts

Public ContactDingjun Hao

Honghui Hospital,Xi'an Jiaotong University School of Medicine

haodingjun@126.com+86 13909297839

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026