Major Depressive Disorder and Bipolar Disorder
Conditions
Interventions
Combined treatment:tDCS 12 sessions (2mA, 20 minutes, F3 anodal, F4 cathodal) over 4 weeks+ simultaneous mindfulness practices
tDCS only:tDCS 12 sessions (2mA, 20 minutes, F3 anodal, F4 cathodal) over 6 weeks
Sponsors
Department of Health, Taipei City Government
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. Aged 20 to 65; 2. Capable of understanding the study procedure and performing informed consent; 3. Fixed regimen of psychotropics for at least 4 weeks; 4. Received diagnosis of DSM-IV major depressive disorder or bipolar disorder; 5. Scoring 20 or above on ?Montgomery-Asberg Depression Rating Scale.
Exclusion criteria
Exclusion criteria: 1. Intellectual disability; 2. Received diagnosis of schizophrenia or substance use disorders; 3. Scoring over 12 on Young Mania Rating Scale; 4. Cerebrovascular or cardiovascular diseases; 5. Metal implants in the body, such as clips and pacemakers; 6. Previous depressive episode refractory to ECT; 7. Pregnant women; 8. Scalp allergic to helmet and electrodes of tDCS device; 9. Head trauma or infection; 10. Intracranial space-occupying lesions, meningitis or encephalitis, with brain surgeries; 11. Plan to receive brain surgery during the study period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cogstate computerized cognitive battery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Montgomery-Asberg Depression Rating Scale;Beck Depression Inventory (BDI);Beck Anxiety Inventory (BAI);Starkstein Apathy Scale;Physical Symptoms Inventory; | — |
Countries
China
Contacts
Public ContactChin-Lun Hung
Taipei City Hospital, Songde Branch
Outcome results
None listed