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A radomized controlled trial of radiofrequency ablation in the treatment of benign thyroid nodules.

A radomized controlled trial of radiofrequency ablation in the treatment of benign thyroid nodules.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-INR-16007884
Enrollment
Unknown
Registered
2016-02-02
Start date
2016-02-02
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

benign thyroid nodules

Interventions

group of microfrequency ablation:treatment of microfrequency ablation

Sponsors

Department of Ultrasound, the 3rd affiliated hospital of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. solid nodule or predominantly (>20%)solid nodule; 2. maximum diameter of the largest nodule > 4cm, other nodules' maxmimum diameter =18years; 6. nodules according to one of the following items below: (1) nodules increased significantly (volume increases more than 50% within 1 year,or at least two diameters of the nodule increase over 20% and it more than 2 mm long]); (2) patients with nodules significantly related symptoms (such as: foreign body sensation, neck discomfort or pain); (3) nodules obviously convex affect the appearance and require treatment; (4) ideological concerns of patients too heavy to affect normal life and denial of clinical observation.

Exclusion criteria

Exclusion criteria: 1. the follicular nodules; 2. abnormal founction of contralateral vocal cord; 3. severe coagulation disorders; 4. severe cardiac or pulmonary disease, too poor to tolerate operation; 5. pregnancy status; 6. large calcification that affect the observation of the nodules; 7. along with hyperthyroidism or hypothyroidism.

Design outcomes

Secondary

MeasureTime frame
Partial Response;Progressive Disease;Stable Disease;Volume Decreased Rate;Thyroid Function;Complication;Cosmetic Scores;Depression Scale;Adverse Reaction;

Primary

MeasureTime frame
complete response;

Countries

China

Contacts

Public ContactJie Ren
renjieguangzhou@126.com+86 13925155583

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 16, 2026