Breast Cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients (18 to 60 years) with American Society of Anesthesiologists (ASA) Physical Status class I-II scheduled for first modified radical mastectomy were included in the study.
Exclusion criteria
Exclusion criteria: 1. Chronic ethanol, long-term use of psychotropic drugs (e.g. sedative drugs and antidepressant); 2. Contraindications for Paravertebral block including coagulopathy, infection at the puncture site, trauma or history of spine surgery; 3. Unable to cooperate with this research due to cognitive impairment, psychopathy or not willing for the hospital follow-up; 4. Administration of other test drugs or joining in other clinical study in 3 months before our study; 5. Received radiotherapy or chemotherapy before surgery; 6. Other conditions not allocated for this study out of the researchers consideration.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Chronic pain intensity; | — |
Secondary
| Measure | Time frame |
|---|---|
| The immune function;Postoperative pain intensity; | — |
Countries
China