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Value of mild sedation on the sedative effects and inflammatory factor level of critically ill patients undergoing multiple trauma

Value of mild sedation on the sedative effects and inflammatory factor level of critically ill patients undergoing multiple trauma

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-INR-15007380
Enrollment
Unknown
Registered
2015-11-07
Start date
2015-12-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

polytrauma

Interventions

mild sedation group:mild sedation
Conventional sedation group:Conventional sedation

Sponsors

Critical Care Medicine Unit, the Affiliated People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 58 patients undergoing multiple trauma were randomized into mild sedation group (the intervention group, n=30) and Conventional sedation group (the control group, n=28) in Critical Care Medicine Unit, the Affiliated Peoples Hospital.

Exclusion criteria

Exclusion criteria: Age <18 years old, pregnancy, severe craniocerebral injury (GCS< 8 points), drugs, dying anesthesia patients with expected life cycle < 30d, A-2 agonists agent or blocker use in patients with contraindications

Design outcomes

Primary

MeasureTime frame
APACHE ?;SOFA;mechanical ventilation;length of ICU stay;multiple organ failure;CRRT;sepsis;accidental extubation;tracheotomy;serum levels of IL-6, TNF-alpha, CRP;mortality;—

Contacts

Public ContactLi Yong
yzliyong0304@126.com+86 13921905600

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026