the patients with mild depressive mood after percutaneous coronary intervention
Conditions
Interventions
1:Drug group
2:Simulated drugs group
3:antidepressant
Sponsors
The first clinical medical college of Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. accord with the diagnostic criteria of TCM syndrome differentiation of depression; 2. accord with the diagnostic criteria of depressive episode of Western medicine; 3. HAMD Depression Scale (24 items), scoring more than 8 cent, less than 35 points; 4. has been performed coronary heart disease PCI surgery; 5. the vital signs are stable, the consciousness is clear, has certain expression ability; 6. aged 18-80 years old, willing to try and cooperate with patients, men and women are not limited; 7. the informed consent, volunteer subjects. The process of obtaining informed consent shall be in accordance with the provisions of the GCP (drug clinical trial management specification).
Exclusion criteria
Exclusion criteria: 1. There are serious suicide; 2. Because of the low degree of culture, language differences, disturbance of consciousness, dementia, aphasia, deafness, agnosia influence emotional expression and not according to the prescribed medication; 3. patients with severe or unstable heart, liver, kidney, endocrine, thyroid dysfunction, blood and other diseases in the Department of internal medicine; 4. had a history of epilepsy, cerebral trauma; 5. alcohol and drug dependence in a year; 6. secondary to other mental illness or physical disease of the depressive episode; 7. with other serious psychiatric symptoms, such as hallucinations, paranoia and other symptoms; 8. pregnant women who are pregnant, pregnant, or likely to be pregnant during the trial; 9. of the superconducting transdermal medicine for treating drug components and paroxetine hydrochloride have allergic history; 10. in 30 days to participate in clinical trials of other drugs; 11. can not take the medicine according to the doctor's advice.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 5-HT content;HAMD Depression Rating Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Seattle angina questionnaire scale; | — |
Countries
China
Contacts
Public ContactWang zhen
Outcome results
None listed