Skip to content

Nerve block anesthesia and general anesthesia influnce postoperative on cognitive dysfunction after hip athroplasty of aged fracture of neck of femur patients: randomized controlled trial

Nerve block anesthesia and general anesthesia influnce postoperative on cognitive dysfunction after hip athroplasty of aged fracture of neck of femur patients: randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-INC-16009960
Enrollment
Unknown
Registered
2016-11-22
Start date
2017-06-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

fracture of neck of femur

Interventions

case group A:nerve block anesthesia and perioperative analgesia
control2:Non nerve block anesthesia
case group B:nerve block anesthesia without perioperative analgesia

Sponsors

Orthopaedics of Shanghai 10th Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Unilateral femur neck fracture patient aged 60-80 years, male and female; 2. Accept the hip arthroplasty treat femur neck fracture, and accept the RCT, sign the informed consent; 3. Without the disease required for THA such as sever osteoarthritis, developmental dysplasia of the hip, femoral head necrosis. Without the disease which affect the prognostic evaluation such as rheumatoid arthritis, thrombocytopenic purpura, Charcot arthropathy; 4. Without the internal medicine diseases such as respiratory system disease; 5. Without nervous-mental system disease, preoperative cognitive function is normal.

Exclusion criteria

Exclusion criteria: 1. The patients with the internal medicine diseases which affect the prognosis; 2. The femur neck fracture patients cannot accept the hip arthroplasty; 3. Reject the nerve block anesthesia; 4. With the joint disease which will affect the prognosis; 5. With mental disease or other disease affect the cognitive function; 6. Cannot cooperate with the follow up visit.

Design outcomes

Primary

MeasureTime frame
occurring of the delirium;harris score;MMSE score;bispectral index, BIS;S100B protein;ions level of serum (Cu, Mg, Zn);cerebral oxygen desaturation, rSO2;

Countries

China

Contacts

Public ContactKun Tao

Orthopaedics of Shanghai 10th Hospital

doctk@163.com+86 13764001236

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026