coronary heart disease
Conditions
Interventions
Group A:infusion of magnesium sulfate
Group C:Infusion of normal saline
Sponsors
North China Grid Company Limited Beijing Electric Power Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The patients aged 30-65 who undergoing elective coronary bypass graft without cardiopulmonary bypass.
Exclusion criteria
Exclusion criteria: 1. Underlying heart failure (right sided or left sided, including low left ventricular ejection fraction, ie. preoperative LVEF < 25%); 2. Underlying renal disease; 3. Underlying diabetes mellitus; 4. Underlying uncontrolled hypertension; 5. Underlying thyroid problems (hypo/hyperthyroidism, active or controlled); 6. Underlying malabsorption (active or controlled); 7. Underlying untreated arrhythmias; 8. Underlying inflammatory disease (active or controlled); 9. Underlying uncorrected magnesium or calcium abnormalities, Emergent or urgent CABG; 10. Patient refusal to enter or continue study; 11. QTc interval abnormalities (including Torsades de pointes syndrome); 12. Co-administration of steroids, statins, aspirin/anti-inflammatory agents.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Th1;Th2;Th3;Th17; | — |
Countries
China
Contacts
Public ContactGuoyan Li
Outcome results
None listed