Tuberculosis
Conditions
Interventions
experimental group:Interleukin 2
Sponsors
Beijing Chest Hospital affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. To be willing and able to give informed consent to participate in the trial treatment and follow-up (signed or witnessed consent if the patient is illiterate); 2. Aged 18-65 years; 3. Chest X-ray showed that there were active tuberculosis foci in the lungs with one of the following cases: (1) sputum specimens (or sputum and bronchial lavage fluid) were 2+ once or 1+ twice; (2) sputum smear positive and sputum X-pert positive. 4. Newly diagnosed cases receiving anti-TB treatment for less than one month; 5. No other immune preparations (such as: thymosinIFN-yBCG-PSNMycobacterium vaccaeUtilinslentinan )were used in the past 3 months; 6. the urine analysis of Women of childbearing age are negative and agree to use the efficient contraception during the study period.
Exclusion criteria
Exclusion criteria: 1. Has a known allergy to any drug of treatment regimens; 2. There are serious complications or impaired renal function (serum creatinine is 1.5 times higher than the normal limit) or impaired liver function (ALT or AST levels are 3 times higher than the normal limit); hemoglobin is less than 7.0g/dl. Platelets less than 50x10^9/L; 3. Complication with Diabetic; 4. The screening diagnosis was isoniazid resistance or rifampin resistance; 5. There are serious cardiovascular diseases, such as heart failure, hypertension, arrhythmia or post myocardial infarction state; 6. Is known to be pregnant or breast-feeding; 7. Karnofsky score is less than 50%; 8. Attending any clinical trial in the past 3 months; 9. with critically ill, and in the judgment of the investigator, not fit for the study or unlikely to complete the full course of study; 10. HIV is positive or AIDS patients; 11. Has Non tuberculous mycobacterial lung disease; 12. Merge with extra pulmonary tuberculosis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| time to conversion;the rate of conversion at the end of the course of treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| adverse reactions;Recurrence rate;the rate of Treatment failure; | — |
Countries
China
Contacts
Public ContactChu Naihui
Beijing Chest Hospital affiliated to Capital Medical University
Outcome results
None listed