Chronic sinusitis
Conditions
Interventions
experimental group:Lizhixue
Control :placebo
Sponsors
EENT Hospital of Fudan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with chronic rhinosinusitis and polyps with multiple Lund-Mackay scores based on CT examination need endoscopic sinus surgery; 2. aged 18-65 years; 3. The researchers have decided that there is no surgical contraindication and no coagulant system disease; 4. Pre operation platelets were normal, PT and APTT were within the normal range of the hospital; 5. The informed consent and the signing of the informed consent.
Exclusion criteria
Exclusion criteria: 1. unilateral (simple left or right) chronic rhinosinusitis and nasal polyps; 2. Those who are known to be allergic to any of the ingredients in this product; 3. A drug (such as EDTA) is being used in the use of a substance containing a calcium binding component; 4. Patients who have used blood clotting drugs 2 weeks before operation; 5. Clinical trials of other research drugs in the near four weeks; 6. Patients with a history of thrombus history or hypercoagulable state; 7. Patients with bleeding tendency or severe blood system disease; 8. systemic diseases such as severe hypertension, tuberculosis, diabetes and liver disease are not controlled, and the researchers believe that they may interfere with diseases such as research or evaluation; 9. abnormal liver function AST, ALT multiple hospital normal range upper limit 1.5 times kidney function abnormal blood creatinine multiple normal upper limit 1.2 times; 10. pregnancy or planned half a year of pregnancy planners and lactation women; 11. Other researchers think it is not suitable for the entry of the group.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoperative bleeding;Operation time; | — |
Countries
China
Contacts
Public ContactWang Dehui
EENT Hospital of Fudan University
Outcome results
None listed