Rhinitis
Conditions
Interventions
experiment group:Weak acid buffered physiological seawater nasal cavity nursing sprayer
control group:Physiological seawater nasal spray
Sponsors
Eye and ENT Hospital of Fudan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) the standard of diagnosis of chronic rhinosinusitis (cpos2012 Kunming standard); (2) aged between 18-65 years; (3) informed consent, voluntary subjects, and signed informed consent.
Exclusion criteria
Exclusion criteria: (1) cold and fever, or for patients with acute rhinitis, acute sinusitis, allergic rhinitis, and severe nasal polyps; (2) the episodes of asthma have been merged and the symptoms are more serious; (3) severe nasal trauma, severe metabolic disorder of sodium chloride and allergies; (4) people under the age of 18 or over 65 years of age, or for women in pregnancy and lactation; (5) there are serious primary cardiovascular diseases, liver diseases, kidney diseases, hematological diseases, lung diseases, or severe diseases that affect their survival, such as cancer or AIDS, and severe hypertension; (6) mentally or legally disabled patients; (7) suspect or indeed have a history of alcohol abuse or drug abuse. Or according to the researchers' judgement, other diseases such as decreasing the possibility of entry or complicating the entry group, such as frequent changes in working environment, are likely to cause loss of visit; (8) a person who is known to be allergic to the composition of the drug in clinical trials; (9) patients who are participating in other clinical trials of drugs; (10) patients with the following combination drugs: glucocorticoids, macrolides, antibacterial agents, mucus dissolving and promoting drainage agents, anti allergic drugs, traditional Chinese medicine and blood reducing agents.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Safety and effecacy; | — |
Countries
China
Contacts
Public ContactDehui Wang
83 Fenyang Road, Shanghai, China
Outcome results
None listed