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Compare of clinical efficacy of traditional endoscopic sequential sclerotherapy plus tissue adhesive injection and endoscopic selective varices devascularization: a multi-center, randomized, and controlled clinical trial.

Compare of clinical efficacy of traditional endoscopic sequential sclerotherapy plus tissue adhesive injection and endoscopic selective varices devascularization: a multi-center, randomized, and controlled clinical trial.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IIR-17013789
Enrollment
Unknown
Registered
2017-12-08
Start date
2018-01-01
Completion date
Unknown
Last updated
2018-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

esophageal and gastric varices

Interventions

group A:traditional endoscopic sequential sclerotherapy plus tissue adhesive injection
group B:Endoscopic selective varices devascularization

Sponsors

The Second Affiliated Hospital of GuangXi Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients were diagnosed with esophageal and gastric varices by preoperative gastroscopy; 2. Esophagogastric variceal bleeding or red color sign was diagnosed by preoperative gastroscopy; 3. Esophageal variceal ligation, sclerotherapy or tissue adhesive injection was not done before; 4. Surgical shunt or disconnection was not done before; 5. Compliance of patients should be well and subsequent visit at 1 months, 3 months, 6 months after the operation on time.

Exclusion criteria

Exclusion criteria: 1. Gastroscopy is routine to exclude contraindications such as hemorrhage caused by gastroduodenal disease, esaphagus straitness and so on; 2. A current diagnosis or medical history of a serious primary disease, such as the disease of heart, blood vessel, kidney, and hematopoietic system; 3. Women of pregnancy, lactation or preparation for pregnancy; 4. Patients of uncontrolled hepatic encephalopathy or uncorrected hemorrhagic shock; 5. Exclude the patients of regional varicose gastric fundus vein.

Design outcomes

Primary

MeasureTime frame
Eradication rate of esophageal and gastric varices;Protection rate of esophageal and gastric varices;

Secondary

MeasureTime frame
Bleeding rate of esophageal and gastric varices;Bleeding rate of peptic ulcer discharging tissue glue;Incidence of chest discomfort;Incidence of portal hypertensive gastropathy;mortality;

Countries

China

Contacts

Public ContactJie'an Huang

The Second Affiliated Hospital of Guangxi Medical University

hjagxmu@163.com+86 13471181378

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026