chest pain (Qi deficiency and blood stasis type)
Conditions
Interventions
experimental group :Qishen capsule + atorvastatin
Sponsors
Department of pharmacy, Anzhen Hospital of Capital Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Signed the informed consent; 2. Aged 30-70 years; 3. chest pain( Qi deficiency and blood stasis type); 4. dyslipidemia:2.266.2mmol/L and LDL-C=3.37mmol/L,or HDL-C1.5mm, protruding into the lumen and clear boundary; 7. ultrasound: 30%=carotid artery diameter stenosis rate =50%.;Inclusion criteria: 1. Signed the informed consent; 2. Aged 30-70 years; 3. chest pain( Qi deficiency and blood stasis type); 4. dyslipidemia:2.266.2mmol/L and LDL-C=3.37mmol/L,or HDL-C1.5mm, protruding into the lumen and clear boundary; 7. ultrasound: 30%=carotid artery diameter stenosis rate =50%.
Exclusion criteria
Exclusion criteria: 1. grade three hypertension group (severe), high risk of diabetes, acute heart failure, stroke, acute myocardial infarction, valvular heart disease, hypertrophic cardiomyopathy, unstable carotid plaque, revascularization or unstable patients with ACS secondary to other causes of unstable angina, peripheral vascular disease, its autoimmune diseases, blood diseases, malignant tumors, infectious diseases and patients with major surgery or trauma; 2. and the expected use of fibrates, ezetimibe and lipid-lowering effects of food supplements and other health products with additives; 3. use and expect more than 2 kinds of antihypertensive drugs (containing 2 kinds of antihypertensive drugs) or 2 or more kinds of hypoglycemic agents (2 kinds); 4. To be expected to use the blood stasis class containing ingredients of Chinese medicine drugs; 5. patients taking warfarin; 6. known to have allergies or allergies to components of the drug; 7. pregnant, lactating and pregnant planners; 8. drug abusers, alcoholics; 9. participated in other clinical studies in the past 1 months; 10. the researchers considered that the participants were not suitable for the experiment.;Exclusion criteria: 1. grade three hypertension group (severe), high risk of diabetes, acute heart failure, stroke, acute myocardial infarction, valvular heart disease, hypertrophic cardiomyopathy, unstable carotid plaque, revascularization or unstable patients with ACS secondary to other causes of unstable angina, peripheral vascular disease, its autoimmune diseases, blood diseases, malignant tumors, infectious diseases and patients with major surgery or trauma; 2. and the expected use of fibrates, ezetimibe and lipid-lowering effects of food supplements and other health products with additives; 3. use and expect more than 2 kinds of antihypertensive drugs (containing 2 kinds of antihypertensive drugs) or 2 or more kinds of hypoglycemic agents (2 kinds); 4. To be expected to use the blood stasis class containing ingredients of Chinese medicine drugs; 5. patients taking warfarin; 6. known to have allergies or allergies to components of the drug; 7. pregnant, lactating and pregnant planners; 8. drug abusers, alcoholics; 9. participated in other clinical studies in the past 1 months; 10. the researchers considered that the participants were not suitable for the experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| carotid plaque;Symptom score of TCM;;carotid plaque;Symptom score of TCM; | — |
Secondary
| Measure | Time frame |
|---|---|
| TC, TG, LDL-C, HDL-C;Biomarker;;TC, TG, LDL-C, HDL-C;Biomarker; | — |
Countries
China
Contacts
Public ContactYang Lin;Yang Lin ;
Beijing Anzhen Hospital of Capital Medical University;Beijing Anzhen Hospital of Capital Medical University
Outcome results
None listed