Dyslipidemia
Conditions
Interventions
Intervention group:Oral intake probiotics, Lactobacillus paracasei N1115
Control group:Oral intake placebo
Sponsors
Peking University Health Science Center
Eligibility
Sex/Gender
All
Age
35 Years to 65 Years
Inclusion criteria
Inclusion criteria: Aged 35~65 years old, total cholesterol=5.18 mmol/L(or 200mg/dL) and <6.99 mmol/L(270mg/dL);Inclusion criteria: Aged 35~65 years old, total cholesterol=5.18 mmol/L(or 200mg/dL) and <6.99 mmol/L(270mg/dL);Inclusion criteria: Aged 35~65 years old, total cholesterol=5.18 mmol/L(or 200mg/dL) and <6.99 mmol/L(270mg/dL);Inclusion criteria: Aged 35~65 years old, total cholesterol=5.18 mmol/L(or 200mg/dL) and <6.99 mmol/L(270mg/dL);Inclusion criteria: Aged 35~65 years old, total cholesterol=5.18 mmol/L(or 200mg/dL) and <6.99 mmol/L(270mg/dL)
Exclusion criteria
Exclusion criteria: Inability to complete study, lactose intolerance, allergic to cow milk, severe digestive system disease, pregnant or nursing women, severe heart or brain disease, diabetes, hepatic disease, renal disease, any disease in blood system, cancer, mental disorders, memory problems and use of hypolipidemic drugs or other functional food.;Exclusion criteria: Inability to complete study, lactose intolerance, allergic to cow milk, severe digestive system disease, pregnant or nursing women, severe heart or brain disease, diabetes, hepatic disease, renal disease, any disease in blood system, cancer, mental disorders, memory problems and use of hypolipidemic drugs or other functional food.;Exclusion criteria: Inability to complete study, lactose intolerance, allergic to cow milk, severe digestive system disease, pregnant or nursing women, severe heart or brain disease, diabetes, hepatic disease, renal disease, any disease in blood system, cancer, mental disorders, memory problems and use of hypolipidemic drugs or other functional food.;Exclusion criteria: Inability to complete study, lactose intolerance, allergic to cow milk, severe digestive system disease, pregnant or nursing women, severe heart or brain disease, diabetes, hepatic disease, renal disease, any disease in blood system, cancer, mental disorders, memory problems and use of hypolipidemic drugs or other functional food.;Exclusion criteria: Inability to complete study, lactose intolerance, allergic to cow milk, severe digestive system disease, pregnant or nursing women, severe heart or brain disease, diabetes, hepatic disease, renal disease, any disease in blood system, cancer, mental disorders, memory problems and use of hypolipidemic drugs or other functional food.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total cholesterol;Triglyceride;low density lipoprotein cholesterin;high density lipoprotein cholesterin;Apo-A;Apo-B; | — |
Secondary
| Measure | Time frame |
|---|---|
| Body weight;waistline;hipline;body fat percentage;Gut microbiota; | — |
Countries
China
Contacts
Public ContactYumei Zhang;Yumei Zhang;Yumei Zhang;Yumei Zhang;Yumei Zhang ;;;;
Peking University;Peking University;Peking University;Peking University;Peking University
Outcome results
None listed