Cervical Cancer
Conditions
Interventions
3D-CRT+DDP:using 3D-CRT technique
IMRT+DDP:using IMRT technique
IMRT+TP:using TP chemotherapy regimen
Sponsors
Tumor Hospital of Shantou University Medical College
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients with cervical cancer confirmed by histology or cytology; 2. Patients with International Federation of Gynecology and Obstetrics (FIGO 2009) stage III staged by at least one gynecological oncologist (associate chief physician or higher), and they were confirmed by image test such as CT or MRI; 3. Patients who had no prior anti-cancer treatment; 4. Patients who have at least one measurable lesion (at least 10mm*10mm in MRI scan of pelvis); 5. Aged 18 to 70 years; 6. ECOG performance status 0 - 2; 7. Weight >=40KG; 8. WBC >=4.0*10^9/L, Hemoglobin>=90g/L, Platelets >=100.0*10^9/L; Bilirubin <=ULN; ALT and AST and ALP<=2.5*ULN; BUN <=1.5*ULN; Creatinine<=1.5*ULN; 9. Signed study-specific informed consent.
Exclusion criteria
Exclusion criteria: 1. Any previous chemotherapy, radiotherapy or surgery for this tumour; 2. Para-aortic nodal involvement or evidence of distant metastasis; 3. Patients who have severe uncontrolled internal diseases or acute infection; 4. Patients who are pregnant or lactating; 5. Patients who did not sign study-specific informed consent; 6. Patients with other invasive malignancies within the last 5 years.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Acute hematological toxicity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Acute gastrointestinal toxicity;Other chronic treatment-related toxicity rate;1-year local control rate; | — |
Countries
China
Contacts
Public ContactXIE LIANGXI
Tumor Hospital of Shantou University Medical College
Outcome results
None listed