non-alcoholic fatty liver disease
Conditions
Interventions
control group :control starch
Sponsors
Shanghai Jiao Tong University Affiliaated Sixth People's Hospital
Eligibility
Sex/Gender
All
Age
30 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Chinese people; 2. Aged 30-40 years old without statistical differences between genders; 3. BMI: not less than 25kg/m2 4. Subjects with nonalcoholic fatty liver disease diagnosed by ultrasonic examination; 5. Written informed consents must be obtained.
Exclusion criteria
Exclusion criteria: 1. Subjects with diabetes mellitus; 2. Subjects with an alcohol consumption history of more than 20 g per day for men and more than 10 g per day for women; 3. Subjects with acute or chronic gastrointestinal diseases; 4. Pregnant, breastfeeding women or women planning to get pregnant are excluded; 5. Subjects suffering diseases or those who have consumed antibiotics within 3 weeks before participation in the trial; 6. Subjects with hepatic virus infections, autoimmune liver disease, Wilson's disease, or other liver diseases will be ruled out; 7. Subjects with hyperthyroidism or hypothyroidism; 8. Subjects with uncontrolled hypertension; 9. Subjects with coagulation abnormalities; 10. Subjects prescribed with drugs or other Chinese or western medicines (except for regular contraceptives); 11. Subjects expected to have poor compliance; 12. Subjects who have used weight loss medication or program in the previous 4 weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gastrointestinal Metabolic Function and Microbiota; | — |
Secondary
| Measure | Time frame |
|---|---|
| hepatic steatosis;liver enzymes;hepatic pathology;anthropometric indexes;body fat;lipid profiles;biochemical indexes; | — |
Countries
China
Contacts
Public ContactWeiping Jia
Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Outcome results
None listed