Efficacy of Postoperative Prophylactic Radiation After Surgery for Positive Circumferential Resection Margin in Esophageal Cancer

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IIR-17012343

Enrollment

Unknown

Registered

2017-08-12

Start date

2017-09-01

Completion date

Unknown

Last updated

2017-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal Cancer

Interventions

experimental group:Surgery+Postoperative prophylactic radiation

control group:Surgery alone

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients with thoracic esophageal cancer who received R0 operations in Fudan University Shanghai Cancer Center and postoperative pathology: squamous cell cancer,positive Circumferential Resection Margin(CRM) 1. KPS=70 before radiotherapy; 2. Did not receive neoadjuvant or adjuvant treatment; 3. No clear recurrent or metastatic lesions before radiotherapy; 4. Intensity modulated radiation therapy(IMRT) is accepted; 5. Regular follow-up.

Exclusion criteria

Exclusion criteria: 1. Exploratory thoracotomy or palliative surgery; 2. No clear recurrent or metastatic sites; 3. Recurrence or metastasis is not certain; 4. Death of no definite cause; 5. Irregular follow-up.

Design outcomes

Primary

Measure	Time frame
Disease-Free Survival Time (DFS);Overall Survival Time (OS);	—

Countries

China

Contacts

Public ContactJiaqing Xiang

Department of Thoracic Surgery, Fudan University Shanghai Cancer Center

j.q.xiang@hotmail.com+86 13901992249

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026