Cough variant Asthma
Conditions
Interventions
trial group:Procaterol Hydrochloride and Montelukast
Sponsors
Beijing Children’s Hospital ,Capital Medical University
Eligibility
Sex/Gender
All
Age
2 Years to 14 Years
Inclusion criteria
Inclusion criteria: 1. Male and female patients aged 2-14 yeas; 2. Physician -diagnosed cough-variant asthma from its symptoms and conditions;cough duration >4weeks,cough or with a white phlegm, cough as the main clinical symptoms or only symptoms, cough at night and (or )the early morning, cough will aggravate after exercise or contact with cold air, without wheeze and fever or antibiotic was ineffective after a long period treatment. 3.Chest X-ray:without obvious abnormalities; 4.Effective response to prior 3days diagnostic treatment with Procaterol. 5.Ask for the medical history in order to exclude postinfectious cough and UACS
Exclusion criteria
Exclusion criteria: 1. Patients are with heart, lung, liver, kidney and other organic disease; 2. Patients have history of upper respiratory tract infection, interstitial pneumonia, pulmonary tuberculosis and other medical diseases in the past 2 months; 3. Oral and inhaled corticosteroids were taken within the past 2 weeks; 4. Patients have participated in other clinical trials in the past 3 months; 5. Patients have adverse reactions to the study drugs; 6. Patients cannot comply with the study protocol; 7. Investigators judged patients who were not eligible for this clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cough score; | — |
Secondary
| Measure | Time frame |
|---|---|
| LCQ questionnaire;Cough recurrence rate;Cough improvement rate; | — |
Countries
China
Contacts
Public ContactZhang Yanhong
Zhejiang Otsuka Pharmaceutical Co., Ltd
Outcome results
None listed