lung protection
Conditions
Interventions
Endotracheal intubation conventional ventilation group:Endotracheal intubation
Endotracheal intubation conventional ventilation group:conventional ventilation
Endotracheal intubation protective ventilation group:Endotracheal intubation
Endotracheal intubation protective ventilation group:protective ventilation
Laryngeal mask conventional ventilation group:Laryngeal mask
Laryngeal mask conventional ventilation group:conventional ventilation
Laryngeal mask protective ventilation group:Laryngeal mask
Laryngeal mask protective ventilation group:protective ventilation
Sponsors
Department of Anesthesiology, Chengdu Military General Hospital,
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. patients accepting general anesthesia for abdominal surgery about stomach,intestine,kidney,liver and gastrointestinal with laparoscopic assisttime,time of operation in 1-4 hours,postoperative need to pull out the endotracheal tube; 2. ASA I-II; 3. aged 18 to 65 years old, male or female, body mass index 18 to 30 kg/m2; 4. no history of serious cardiovascular diseases (such as coronary heart disease or congenital heart disease, cardiac function level 3 above, etc.); 5. No nervous system disorders, can normal verbal communication; 6. no history of severe allergic; 7. Women of child-bearing age should be negative pregnancy test; 8. Voluntary patients with general anesthesia and participate are in the study.
Exclusion criteria
Exclusion criteria: 1. allergies to the general anesthetics and other intraoperative medication; 2. long-term application of narcotic analgesics , sedatives or nonsteroidal anti-inflammatory drugs; 3. people have history of neuromuscular disease,endocrine system disease,allergic disease or incomplete function of liver and kidney; 4. patients with preoperative pulmonary function severe damaged need postoperative respiratory support ; 5. patients whose intraoperative blood is greater than 20% of the blood volume or who need second operation; 6. Participation in the other drug clinical researchers nearly three month; 7. Researchers think who is not suitable for participantiond.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| operation time;volume of input and output; | — |
Primary
| Measure | Time frame |
|---|---|
| pulmonary complications;blood pressure;heart rate;perioperative SpO2;EtCO2;airway pressure;blood gas analysis;body temperature;respiratory rate;lung auscultation;cough;expectoration;chest X-ray;the hospital total number of days;the satisfaction of patients; | — |
Countries
China
Contacts
Public ContactWei Wu
Chengdu Military General Hospital
Outcome results
None listed