The Dose-response study of Bupivacaine for Cesarean Section under Combined spinal-epidural Anesthesia when Prophylactic Infusion of Phenylephrine

Effect of Prophylactic Infusion of Phenylephrine on the ED50 of Intrathecal Hyperbaric Bupivacaine for Cesarean Section:A Prospective Randomized Study.

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IIR-17011824

Enrollment

Unknown

Registered

2017-07-01

Start date

2017-07-03

Completion date

Unknown

Last updated

2017-07-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cesarean section

Interventions

Trial Group:phenylephrine

Control Group:saline

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: healthy patients with ASA status ? or ??, who required to have an elective cesarean section, were enrolled in this study.

Exclusion criteria

Exclusion criteria: Exclusion criteria as follows: patients with a body mass index (BMI) > 35 kg/m2; any complication to local anesthesia, including coagulopathy and local or general infection; obstetrics issues such as pre-eclampsia, ruptured membranes, gestational age less than 37 weeks, cesarean section history, early or active labor, intrauterine growth restriction; coexisting disease including diabetes or hypertension.

Design outcomes

Primary

Measure	Time frame
ED50;	—

Secondary

Measure	Time frame
side effects;	—

Countries

China

Contacts

Public ContactFEI XIAO

Jiaxing University Affiliated Women and Children Hospital

13706597501@163.com+86 13706597501

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026