Primary osteoarthritis of knee undergoing total knee replacement
Conditions
Interventions
Group 1:Single shot saphenous nerve block
Group 2:Continuous saphenous nerve block
Sponsors
Department of Anaesthesia and Intensive Care, Pok Oi Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 79 Years
Inclusion criteria
Inclusion criteria: 1. Primary, unilateral total knee replacement under central neuroaxial block; 2. Aged 18 to 80 years; 3. American Society of Anesthesiologists (ASA) physical status I – III.
Exclusion criteria
Exclusion criteria: 1. Patients with secondary osteoarthritis of the knee; 2. Patients undergoing operation under general anaesthesia; 3. Pregnancy; 4. Body weight 40 kg/m2; 5. Allergy to opioid or local anaesthetics; 6. Patients with contraindications to COX-2 inhibitors use; 7. Chronic opioid use (> 1 month of 60mg morphine oral equivalents daily); 8. Subject refusal.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score at rest, active flexion and during physiotherapy session on postop day 1, day 2 and day 3;Cumulative fentanyl consumption on postop day 1, day 2 and day 3;Cumulative tramadol consumption on postop day 1, day 2 and day 3; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of nausea and vomiting;Patient satisfaction;Other adverse events such as nerve injury, vascular injury, infection at catheter site, fall; | — |
Countries
China
Contacts
Public ContactChan Chin Chin
Department of Anaesthesia and Intensive Care, Pok Oi Hospital
Outcome results
None listed