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Randomized clinical study of paclitaxel combined with lobaplatin compared to paclitaxel combine with cisplatin in neoadjuvant chemotherapy and sequential concurrent chemoradiotherapy of locally advanced cervical cancer

Randomized clinical study of paclitaxel combined with lobaplatin compared to paclitaxel combine with cisplatin in neoadjuvant chemotherapy and sequential concurrent chemoradiotherapy of locally advanced cervical cancer

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IIR-17011559
Enrollment
Unknown
Registered
2017-06-02
Start date
2017-06-15
Completion date
Unknown
Last updated
2017-06-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical Cancer

Interventions

Observation group:Paclitaxel + lobaplatin
Control group:Paclitaxel +cisplatin

Sponsors

Guizhou Cancer Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Voluntarily participate and sign informed consent; 2. squamous cell carcinoma or adenocarcinoma confirmed Histologically,age between 18 and 70 years; 3. Tumor lesions can be measured by gynecological examination, CT / MRI measurement; 4. KPS=70, survival expectations=6months and Blood, liver and kidney function normal; 5. The treatment is the first course of treatment (no pelvic radiotherapy history, no concurrent chemotherapy history).

Exclusion criteria

Exclusion criteria: 1. Had other malignancies; 2. Patients who have received other drug tests in the past month; 3. Pregnant women or lactating women and treatment of contraception during the observation period of women of childbearing age; 4. Have a serious history of allergies or specific physical; 5. Have severe lung or heart disease.

Design outcomes

Primary

MeasureTime frame
Cervical Cancer Mass;

Countries

China

Contacts

Public ContactRan Li

Guizhou Cancer Hospital

ranli171@hotmail.com+86 13984375768

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 18, 2026