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Phase III Multi-center Trial of Peripheral Nerve Rewiring for Treating Hemiplegic Upper Extremity after Hemorrhagic Stroke

Phase III Multi-center Trial of Peripheral Nerve Rewiring for Treating Hemiplegic Upper Extremity after Hemorrhagic Stroke

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IIR-17011173
Enrollment
Unknown
Registered
2017-04-18
Start date
2017-05-01
Completion date
Unknown
Last updated
2017-04-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemorrhagic Stroke

Interventions

Sponsors

Huashan Hospital affiliated to Fudan University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
35 Years to 60 Years

Inclusion criteria

Inclusion criteria: (1) Spastic hemiplegia following hemorrhagic stroke; (2) MMSE scales scores were above 27, with normal language function ; (3) Fugl-Meyer scales scores were 20-30 points; (4) Male and female aged 35-60 years old; (5) Had received regular rehabilitation therapy for at least 1 years and ceased improving in the paralyzed hand; (6) Could walk independently; (7) Willing to receive therapy to achieve further functional improvement; (8) Central neurologic injury only involving the hemisphere contralateral to the paralyzed hand, as indicated by brain MRI scans; (9) Had received education of Grade four and above.

Exclusion criteria

Exclusion criteria: (1) Presence of severe systemic diseases such as diabetes mellitus or cardiopulmonary diseases, contraindicating surgery; (2) A family history of psychosis, major depression, suicidal ideation, or epilepsy, mental illness, or epilepsy; (3) Presence of severe, fixed contracture or joint deformity; (4) Have received Botulinum toxin injection in 6 monthes before adimission.

Design outcomes

Primary

MeasureTime frame
Fugl-Meyer Scale;

Secondary

MeasureTime frame
Wolf Scale;Modified Ashworth Scale;Muscle Power of the Affected Upper Extremity;Tactile threshold of the Affected Upper Extremity;Range of motion of the joint;MMSE Scale;Hamilton Depression Rating Sc;the MOS item short from health survey, SF-36;

Countries

China

Contacts

Public ContactWendong Xu

Huashan Hospital Affiliated to Fudan University

wendongxu@fudan.edu.cn+86 18916120869

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026