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Clinical study of allogeneic NK cells in the treatment of hepatocellular carcinoma

Phase I/II clinical study of HLA haploidentical NK cells in the treatment of hepatocellular carcinoma

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IIR-17011029
Enrollment
Unknown
Registered
2017-03-31
Start date
2017-04-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatocellular Carcinoma

Interventions

Surgical group:NK cells therapy
Minimally invasive treatment group:NK cells therapy
Advanced liver cancer treatment group:NK cells therapy

Sponsors

302th Hospital infectious disease treatment and research center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. The expected survival of more than 6 months; 2. Patients with surgical resection of HCC patients; 3. Patients with minimally invasive treatment, such as Radiotherapy, chemotherapy, radiofrequency ablation and TACE; 4. Advanced liver cancer patients who can not carry out surgery, radiotherapy and minimally invasive treatment.

Exclusion criteria

Exclusion criteria: 1. Patients with alcohol or intravenous drug addicts in the last year; 2. With any autoimmune disease in patients; 3. At the same time, there are other viral infections, such as HIV; 4. Combined with abdominal infection, hepatic encephalopathy, gastrointestinal bleeding and so on; 5. Allergies, had a history of blood products allergies; 6. Pregnant women, lactating women or estrogen contraceptives; 7. Patients who have been or are using glucocorticoid therapy within six months; 8. Patients who have received other biotherapies within six months; 9. Who are unable or unwilling to provide informed consent or who can not comply with the research request.

Design outcomes

Primary

MeasureTime frame
Survival;Clinical detection;Immunological detection;

Countries

China

Contacts

Public ContactFusheng Wang

Treatment and Research Center for Infectious Diseases, 302 Hospital

fswang302@163.com+86 010-66933332

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026