common cold
Conditions
Interventions
Experimental group:Chlorpheniramine 4 mg + Phenylephrine 10 mg
Control group:Placebo
Sponsors
Faculty of Medicine, Chiang Mai University
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Subjects age 18-45 years old with complaints of common cold not more than 3 days that is diagnosed by general practitioner will be recruited.
Exclusion criteria
Exclusion criteria: Subjects were excluded from the study if: they had underlying diseases in cardiovascular, neuropsychiatric, glaucoma, Thyrotoxicosis, liver, or kidney disorders, and subjects with a history of hypersensitivity to antihistamine/decongestant, who may need long-term antihistamine treatment and used monoamine oxidase inhibitor (MAOI). Patients who complain with nausea, vomiting and diarrhea will be excluded. Subjects must not be used other medications prior study as follows: decongestant for 72 h, first generation antihistamine for 72 h, second generation antihistamine for 5 days, analgesics/antipyretics for 24 h, anti-inflammatory drugs for 72 h, or any GI drugs for 72 h. Neither nasal sprays nor nasal washes was to apply within 48 h prior to study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nasal symptom score, Rhinomanometry, Reaction time, Real-life cognitive function tests; | — |
Countries
Thailand
Contacts
Public Contactsuthunya chupradit
Chiang Mai University
Outcome results
None listed