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Effects of atropine gel and eye drops with different low concentration on pupil size and residual accommodation

Effects of atropine gel and eye drops with different low concentration on pupil size and residual accommodation

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IIR-17010513
Enrollment
Unknown
Registered
2017-01-24
Start date
2017-01-25
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

myopia

Interventions

atropine gel:0.005%,0.01%,0.025%,0.05% atropine gel
atropine eye-drop group:0.005%,0.01%,0.025%,0.05% atropine eye drops

Sponsors

Beijing Tongren Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
22 Years to 25 Years

Inclusion criteria

Inclusion criteria: Aged 22-25 years old; cycloplegic SE: -6.0D to -2.0D; myopia progresses fast(=0.5D last year); distance corrected visual acuity: greater than or equal to 1.0; astigmatism:less than 1.5D; anisometropia: less than 1.0D; normal ocular pressure; without significantly strabismus or other eye diseases; no systemic diseases which may affecting visual development, such as diabetes; without the use of asthma drugs during the last year; having signed the informed consent.

Exclusion criteria

Exclusion criteria: Those who can't tolerate eye examinations; those with contraindication to atroppine; those with eyes visual function defects or stereo visual defects; those with the applying history of atropine or pirenzepine; those who are unable to voluntarily participate in this study; those who are allergic to atropie, cyclopentanone, proxymetacaine or benzalkonium chloride.

Design outcomes

Primary

MeasureTime frame
pupil size;residual accommodative amplitude;distant visual acuity;

Countries

China

Contacts

Public ContactLi Shiming

Beijing Tongren Hospital

lishiming81@163.com+86 13691557986

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026