Comparison of Rapid IV Bolus and Intranasal Adminstration of Dexmedetomidine for Treatment and Prophylaxis of Emergence Agitation in Anesthetized Pediatric Patient

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IIR-16010263

Enrollment

Unknown

Registered

2016-12-27

Start date

2016-12-01

Completion date

Unknown

Last updated

2017-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Emergence-Agitation in Anesthetized

Interventions

DV group:in vein rapid bolus adminstration of dexmedetomidine 0.5mg/kg

DN1 group:intranasal adminstration of dexmedetomidine 1ug/kg

DN2 group:intranasal adminstration of dexmedetomidine 2ug/kg

Eligibility

Sex/Gender

All

Age

5 Years to 10 Years

Inclusion criteria

Inclusion criteria: 1. ASA 1 or 2, aged 5-10 years; 2. Have complete clinical data; 3. Obtain informed consent of patient or guardian.

Exclusion criteria

Exclusion criteria: 1. Body weight out of 10 ~ 40kg 2. Airway abnormalities, upper respiratory tract infection, bronchial asthma, allergic to dexmedetomidine, arrhythmias, congenital heart disease, mental disorders, autism or other disorders of psychological development history

Design outcomes

Primary

Measure	Time frame
Systolic Blood Pressure;Diastolic Blood Pressure;Heart Rate;	—

Secondary

Measure	Time frame
Incidence of Emergence Agitation;the score of RASS at PACU;	—

Countries

China

Contacts

Public ContactXU Jin

Plastic Surgery Hospital,CAMS, PUMC

251456663@qq.com+86 13699126208

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026