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The protective effect of hydrogen on early brain injury in patient after subarachnoid hemorrhage

The protective effect of hydrogen on early brain injury in patient after subarachnoid hemorrhage

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IIR-16009220
Enrollment
Unknown
Registered
2016-09-18
Start date
2016-12-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

subarachnoid hemorrhage

Interventions

Treatment group:Oral hydrogen-rich water
control group:Oral regular water

Sponsors

Department of Neurosurgery, Jinling Hospital, School of Medicine, Nanjing University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Aged 20 to 80 years old, aneurysm rupture, Hunt and Hess grade III or IV, aneurysm treated by interventional embolotherapy within 72 hours after SAH, and written informed consent from the patient or family member.

Exclusion criteria

Exclusion criteria: Severe brain edema, heart dysfunction, renal insufficiency, Fisher grade IV, and rejection of randomization.

Design outcomes

Primary

MeasureTime frame
brain computed tomography;Malondialdehyde;neuron-specific enolase(NSE );S-100 calcium binding protein B;Glasgow Coma Scale;—

Secondary

MeasureTime frame
Transcranial color Doppler;C-reactive protein;—

Countries

China

Contacts

Public ContactXin Zhang

Jinling Hospital, School of Medicine, Nanjing University

zhangxsp@163.com+86 13851879970

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026