knee osteoarthritis,OA
Conditions
Interventions
Conventional western medicine treatment group:Sodium hyaluronate injection
Traditional Chinese medicine treatment group: Overcoating and Medical Treatment
Chinese and western medicine treatment group:Overcoating and Medical Treatment
Sponsors
Gansu hospital of TCM
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. in accordance with the western medicine diagnostic criteria and the standard of diagnosis of disease and curative effect of traditional Chinese medicine "wind cold dampness bi, rheumatic fever bi, blood stasis resistance syndrome, liver and kidney deficiency type closed in patients with knee osteoarthritis; 2. Aged 18-75 years, male and female; 3. the research of knee osteoarthritis X-ray evidence for level 1, 2, 3 (Kellgren and Lawrence radiological grading). 45 degree shaft break a class 1, 2, 3; Color ultrasonic class for 1, 2, 3; 4. body mass index (BMI) 35 kg/m2 or less; 5. side of the knee on the ground walk, VAS score between 21-90 - mm; 6. patients with treatment requirements and can finish as planned, and be able to cooperate and follow-up clinical observer; 7. subjects in fully understand the nature of this study, the nature of the disease, a drug of features, relevant treatment and to participate in this study may need to bear the risk, can understand and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. knee other painful inflammatory disease: rheumatism and rheumatoid arthritis, psoriatic arthritis, gout, hemophilia sex arthritis, infectious arthritis, etc.; 2. outside of the knee osteoarthritis knee painful injuries, such as joints of tumor villi nodular synovitis, joint trauma (meniscus tear, ligament injury, bone contusion and cartilage fracture), etc.; 3. inflation), or skin temperature increased significantly or bone mineral density 10 degree, genu valgum > 20 degree deformity and joint gap; 8. cancer patients in recent five years), alzheimer's disease; 9. of the knee osteoarthritis Kellgren and Lawrence radiological grading evidence of 0, 4. 45 degree shaft break a class 4; High frequency color ultrasound class 0 to 4; 10. within 1 month before the test using glucocorticoid hormone drugs or participated in clinical trials of other drugs, participate in the clinical trials have analgesic drugs to be stopped at least a week before can be selected; 11. within 3 months before the experiment research knee joint cavity treatment, including joint, joint cavity flushing, arthroscopic surgery; 12. this test related pharmaceutical ingredients known allergies; 13. other researchers judgment is not suitable for selected participants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| general data;WOMAC pain score;WOMAC rigid score;FDIP of WOMAC;life quality score of SF-12; | — |
Secondary
| Measure | Time frame |
|---|---|
| Color ultrasonic evaluation; | — |
Countries
China
Contacts
Public ContactShenhua Li
Gansu hospital of TCM
Outcome results
None listed